The value of radiotherapy for primary central nervous system lymphoma

VernacularTitle:原发中枢神经系统淋巴瘤放疗价值
Author: Yuan YUAN ¹ ; Suyu ZHU ; Jumei ZHOU
Author Information

1. 湖南省肿瘤医院，腹部/淋巴瘤放疗科，长沙　410000
Keywords: Lymphoma; Central nervous system neoplasms; Whole brain radiotherapy; Autologous hematopoietic stem cell transplantation
From: Chinese Journal of Radiation Oncology 2024;33(6):572-577
CountryChina
Language:Chinese
Abstract: Primary central nervous system lymphoma (PCNSL) is a disease with relatively poor prognosis, and radiotherapy is one of the important treatment methods. However, with the widespread application of high-dose methotrexate-based induction chemotherapy regimen and autologous hematopoietic stem cell transplantation consolidation therapy, as well as the impairment of cognitive function after whole brain radiotherapy, the value of radiotherapy has been controversial in the past decade. This article reviews the application of radiotherapy in various treatment stages of PCNSL, the selection of radiotherapy target area and dose, and discusses the value of radiotherapy in the treatment of PCNSL.