Research progress on the pathogenesis and rehabilitation strategies of radiation-induced muscle fibrosis
10.3760/cma.j.cn112271-20240205-00047
- VernacularTitle:放疗后肌肉纤维化的发病机制及康复治疗策略研究进展
- Author:
Yun LI
1
;
Xixia LIU
Author Information
1. 广西中医药大学，南宁 530219
- Keywords:
Radiation-induced muscle fibrosis;
Transforming growth factor-β;
Connective tissue growth factor;
Cancer-associated fibroblast;
Rehabilitation strategy
- From:
Chinese Journal of Radiological Medicine and Protection
2024;44(11):985-990
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced fibrosis, especially radiation-induced muscle fibrosis (RIMF), is a common complication associated with radiotherapy. After radiotherapy, there is a gradual worsening of muscle stiffness and joint mobility impairments over time, which severely affects the quality of life of cancer patients. This article aims to review the latest research progress on the mechanisms and diagnosis and assessment methods of RIMF, as well as its rehabilitation strategies. This review provides systematic and effective health management and rehabilitation strategies to improve the prognosis of patients with RIMF.
