Clinical application value of rapid arterial spin labeling imaging in brain glioma
10.3760/cma.j.cn112149-20230821-00111
- VernacularTitle:快速动脉自旋标记成像在脑胶质瘤中的临床应用价值
- Author:
Yanling ZHANG
1
;
Murong XU
;
Xiaolu XU
;
Jinli DING
;
Yunyun DUAN
;
Yaou LIU
;
Yuhua JIANG
;
Zhizheng ZHUO
Author Information
1. 首都医科大学附属北京天坛医院放射科，北京 100070
- Keywords:
Magnetic resonance imaging;
Rapid arterial spin labeling;
Brain glioma;
Perfusion imaging
- From:
Chinese Journal of Radiology
2024;58(5):529-533
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the feasibility and clinical diagnostic value of rapid arterial spin labeling (ASL) imaging in brain glioma.Methods:Patients with glioma admitted to Beijing Tiantan Hospital, Capital Medical University from May 2021 to December 2022 were prospectively enrolled. All patients received MR rapid ASL (scan time: 1 min) and conventional ASL (scan time: 4 min 30 s), where the cerebral blood flow (CBF) perfusion maps were obtained. The qualitative analysis of CBF signal intensity and quantitative analysis of average CBF values from both tumor solid and edema regions were conducted by two radiologists independently. Kappa test and intraclass correlation coefficient ( ICC) were used to analyze the consistency of qualitative and quantitative results, respectively. Results:A total of 30 patients with brain glioma were included. The 2 physicians used rapid ASL to determine low perfusion, isoperfusion, and hyperperfusion in the tumor area in 1, 6, 23 cases and 0, 5, and 25 cases, respectively; and used conventional ASL to determine low perfusion, isoperfusion, and hyperperfusion in the tumor area in 0, 9, and 21 cases, respectively. The results of qualitative analysis of rapid ASL and conventional ASL were highly consistent within and between groups ( Kappa was 0.830 and 0.850 respectively). The results of quantitative analysis of rapid ASL and conventional ASL were highly consistent within and between groups ( ICC 0.940—0.994). Conclusion:Rapid ASL with shorter scanning time could be applied in assessing tissue perfusion in brain glioma and contribute to the clinical diagnosis of gliomas.
