Clinical efficacy of AcoStream peripheral thrombus aspiration system combined with catheter-directed thrombolysis in treatment of lower extremity deep vein thrombosis
10.3760/cma.j.cn112149-20230821-00109
- VernacularTitle:应用AcoStream外周血栓抽吸系统联合置管溶栓治疗下肢深静脉血栓形成的临床价值
- Author:
Tao WANG
1
;
Wensheng LOU
;
Haobo SU
;
Cheng QIAN
;
Yinghao LI
;
Guoping CHEN
;
Xu HE
;
Jianping GU
Author Information
1. 南京医科大学附属南京医院（南京市第一医院）介入血管科，南京 210006
- Keywords:
Venous thrombosis;
Lower extremity;
Percutaneous mechanical thrombectomy;
Catheter Directed thrombolysis;
Acostream peripheral thrombus aspiration system
- From:
Chinese Journal of Radiology
2024;58(5):523-528
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy and safety of AcoStream peripheral thrombus aspiration system combined with catheter-directed thrombolysis in the treatment of lower extremity deep vein thrombosis.Methods:The clinical data of 16 lower extremity deep vein thrombosis cases treated with AcoStream peripheral thrombus aspiration system combined with catheter-directed thrombolysis, admitted to the authors′ hospital from May 2022 to November 2022, were retrospectively analyzed. The differences in circumferential diameter between the affected limb and the healthy side, venous patency score, thrombus clearance grade and intraoperative blood loss were observed and compared. The Villalta score was used during the follow up. Paired sample t-test and Wilcoxon rank sum test were used to compare the changes in the observed indicators before and after treatment to evaluate the efficacy. Results:Treatment were successfully performed in all patients. Before treatment, the circumference differences between the affected and unaffected thighs and calves were (3.69±0.97) and (3.34±0.75)cm, respectively, the venous patency score of the affected side was 8(7.25,9) points. After treatment, the circumference differences between the affected and unaffected thighs and calves were (0.81±0.68) and (0.84±0.70)cm, respectively. The venous patency score of the affected side was 1(0,1)points, with statistically significant differences ( P<0.001). Grade Ⅲ thrombus clearance was achieved in 7 patients, grade Ⅱ thrombus clearance was achieved in 9 patients. The average blood loss during thrombus aspiration was (133.1±12.0) ml. Following up for 6 months, the Villalta score was 0(0,1.75) points. Conclusion:Acostream peripheral thrombus aspiration system combined with catheter-directed thrombolysis is safe and effective for the treatment of lower extremity deep venous thrombosis, with satisfactory short-term efficacy and high clinical application value.
