Evaluating the impact of transcatheter mitral valve edge-to-edge repair devices on the assessment of mitral valve regurgitation by echocardiography based on individualized computer fluid models
10.3760/cma.j.cn131148-20240118-00046
- VernacularTitle:个体化计算机流体模型评估经导管二尖瓣缘对缘修复装置对二尖瓣反流超声定量分析的影响
- Author:
Hongning SONG
1
;
Yuanting YANG
;
Mingqi LI
;
Ji ZHANG
;
Jinling CHEN
;
Qing ZHOU
Author Information
1. 武汉大学人民医院超声影像科，武汉 430060
- Keywords:
Echocardiography;
Mitral regurgitation;
Transcatheter edge-to-edge repair;
Computational fluid dynamics
- From:
Chinese Journal of Ultrasonography
2024;33(6):461-467
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the impact of transcatheter edge-to-edge repair (TEER) devices on mitral valve regurgitant flow convergence post-procedure using computational fluid dynamics(CFD), and to seek solutions for accurately measuring effective regurgitant orifice area(EROA) after TEER.Methods:Multimodal fusion was conducted based on preoperative cardiac CT images and intraoperative three-dimensional transesophageal echocardiography(3DTEE) of 33 patients with mitral valve regurgitation undergoing TEER at Renmin Hospital of Wuhan University from January 2020 to August 2023. Using this data, CFD models of mitral valve regurgitation post-TEER, including with and without the TEER device, were constructed. The distance (D) from the midpoint of the mitral regurgitation orifice to the TEER device was measured. The proximal isovelocity surfice area(PISA) radius with and without the TEER device was measured, and the corresponding EROA1 and EROA2 based on this was calculated. The EROA correction factor CC=EROA2/EROA1 was calculated.Results:A total of 42 sets of CFD models with mild or greater residual mitral regurgitation, both with and without the TEER device, and 50 sets of PISA were obtained. Based on the relative position of PISA to the TEER device, four types of PISA were observed: Type 1: PISA away from the TEER device (D>R, 14 cases), with a CC of 0.93±0.07; Type 2: PISA adjacent to the TEER device (D
