Meta analysis of risk factors for pulmonary embolism in patients with spinal injury
10.3760/cma.j.cn501098-20240926-00580
- VernacularTitle:脊柱损伤患者肺栓塞危险因素的Meta分析
- Author:
Yijing LI
1
;
Supeng YAN
;
Xiaoping ZHOU
;
Xiaoli WEN
;
Tianjiao LI
;
Xiangcheng HUANG
;
Wei SUN
Author Information
1. 陆军军医大学第一附属医院急诊医学科，重庆 400038
- Keywords:
Spinal injuries;
Spinal cord injuries;
Pulmonary embolism;
Risk factors;
Meta analysis
- From:
Chinese Journal of Trauma
2024;40(11):1000-1007
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the risk factors for pulmonary embolism in patients with spinal injury.Methods:Literature on risk factors for pulmonary embolism after spinal injury was searched on CNKI, Wanfang database, VIP Chinese Science, PubMed, Embase, Cochrane Library, Up to Date databases from inception through November 2023. A Meta-analysis was performed with the software of RevMan 5.4 after two researchers screened the literature independently according to the inclusion and exclusion criteria, extracted the data and evaluated their quality. Correlations of gender, age, surgical duration, intervertebral disc fusion, body mass index, comorbidity, medicine prophylaxis, deep venous thrombosis (DVT) history, and length of hospital stay with the incidence of pulmonary embolism in patients with spinal injury were evaluated.Results:A total of 10 studies were enrolled, including 2 prospective cohort studies and 8 cross-sectional studies. The total sample size was 401 698 patients, with 525 in the pulmonary embolism group and 401 173 in the non-pulmonary embolism group. The Meta analysis showed that gender ( OR=1.59, 95% CI 1.20, 1.97), age ( OR=1.58, 95% CI 1.19, 2.10), surgical duration ( OR=2.56, 95% CI 1.84, 3.56), DVT history ( OR=15.84, 95% CI 1.88, 133.25) and length of hospital stay ( OR=1.08, 95% CI 1.07, 1.09) were statistically significantly correlated with the incidence of pulmonary embolism in patients with spinal injury ( P<0.01), while intervertebral fusion, body mass index, comorbidity, and medicine prophylaxis were not correlated with the incidence of pulmonary embolism ( P>0.05). Conclusion:Gender, age, surgical duration, DVT history and length of hospital stay are risk factors for pulmonary embolism in patients with spinal injury.
