Research Progress in the Treatment of Non-alcoholic Fatty Liver Disease with Chinese Materia Medica Intervention of Ferroptosis
10.19879/j.cnki.1005-5304.202308423
- VernacularTitle:中药干预铁死亡治疗非酒精性脂肪性肝病研究进展
- Author:
Shanzheng LI
1
;
Wenxia ZHAO
Author Information
1. 河南中医药大学第一临床医学院,河南 郑州 450000
- Keywords:
ferroptosis;
non-alcoholic fatty liver disease;
non-alcoholic steatohepatitis;
Chinese materia medica;
mechanism;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(12):191-196
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis is a unique iron-dependent cell death mode,which directly participates in and affects the occurrence,development and outcome of non-alcoholic fatty liver disease(NAFLD).Inhibiting ferroptosis can effectively prevent and improve liver injury in NAFLD patients.Chinese materia medica and the preparations have good inhibitory effect on liver ferroptosis and can play the role of liver protection.In this article,the pathogenesis of ferroptosis and its role in the evolution of NAFLD were reviewed,and the treatment of NAFLD by Chinese materia medica intervention in different pathways of ferroptosis mechanism was revealed,in order to provide reference for the mechanism research and clinical diagnosis and treatment of NAFLD.
