Content Determination and Analysis of Alkaloid Contents Between Fritillariae Anhuiensis Bulbus and 5 Fritillaria Medicinal Materials
10.19879/j.cnki.1005-5304.202406251
- VernacularTitle:皖贝母与贝母类药材生物碱含量测定与分析
- Author:
Zeqian MA
1
;
Han LUO
;
Hong ZHANG
;
Chengwu FANG
;
Shoujin LIU
Author Information
1. 安徽中医药大学药学院,安徽 合肥 230012
- Keywords:
Fritillariae Anhuiensis Bulbus;
Fritillaria medicinal materials;
UV-spectrophotometry;
UPLC-ELSD;
alkaloid
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(12):136-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the total alkaloids and six alkaloid components,including peimisine,of Fritillariae Anhuiensis Bulbus and five types of Fritillaria medicinal materials;To providebasis for the medicinal use of Fritillariae Anhuiensis Bulbus.Methods The total alkaloid content and 6 alkaloid components(peimisine,sipeimine-3β-D-glucoside,sipeimine,peimine,peiminine and isoverticine)of Fritillariae Anhuiensis Bulbus and 5 medicinal Fritillaria were determined by UV-Spectrophotometry and UPLC-ELSD method,and 18 batches of Fritillaria medicinal materials were classified by clustering analysis and principal component analysis.Results The total alkaloid content of Fritillariae Anhuiensis Bulbus was significantly higher than that of other Fritillarias.The results of clustering and principal component analysis showed that Fritillariae Anhuiensis Bulbus was classified into one class with Fritillariae Thunbergii Bulbus and Fritillariae Hupehensis Bulbus.Conclusion Fritillariae Anhuiensis Bulbus is similar to Fritillariae Thunbergii Bulbus and Fritillariae Hupehensis Bulbus in the composition of alkaloids,which can be used as a medicinal cultivation variety.
