Research Progress in Pharmacological Effects of Zanthoxyli Radix and Prediction and Analysis of Q-markers
10.19879/j.cnki.1005-5304.202310465
- VernacularTitle:两面针药理作用及质量标志物预测分析研究进展
- Author:
Yuan ZHOU
1
;
Yinggang ZENG
;
Qiuxia TAO
;
Yan LIANG
;
Liuping WANG
;
Jianfang FENG
Author Information
1. 广西农业职业技术大学,广西 南宁 530007
- Keywords:
Zanthoxyli Radix;
pharmacological effects;
Q-marker;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(11):180-185
- CountryChina
- Language:Chinese
-
Abstract:
The medicinal history of Zanthoxyli Radix is long,and it is recorded in the Shen Nong Ben Cao Jing under the name of Manjiao.Modern pharmacological research has proven that Zanthoxyli Radix has anti-tumor,antibacterial,antioxidant,and hemostatic effects.This article reviewed the pharmacological effects of Zanthoxyli Radix based on its functional indications.Based on the basic requirements of TCM quality markers(Q-markers),this article predicted and analyzed the Q-markers of Zanthoxyli Radix from the perspectives of plant phylogeny and chemical component specificity,chemical component and pharmacological correlation,and chemical component testability.It is proposed to select alkaloids,flavonoids,and lignans as the Q-markers for the general classification of Zanthoxyli Radix.The candidate components for Q-marker were identified,including chloramphenicol,white croaker alkaloid,magnolian alkaloid,taro alkaloid,vanillin,hesperidin,L-sesamin and L-asarone,providing a reference for further research on the quality standards of Zanthoxyli Radix.
