Exploration on the TCM Pathogenesis of Pulmonary Fibrosis Based on the Theory of"Lung Connecting to Large Intestine"
10.19879/j.cnki.1005-5304.202311341
- VernacularTitle:基于"肺合大肠"理论探讨肺纤维化中医病机
- Author:
Yawei DONG
1
,
2
;
Zhongbo ZHU
;
Fan YANG
;
Quan MA
;
Hongmei LI
;
Yanmei ZHANG
;
Lanlan HE
;
Xuhui ZHANG
;
Xiping LIU
Author Information
1. 甘肃中医药大学甘肃省中医方药挖掘与创新转化重点实验室,甘肃 兰州 730000
2. 甘肃中医药大学甘肃省中药新产品创制工程实验室,甘肃 兰州 730000
- Keywords:
lung connecting to large intestine;
lung and the large intestine being interior-exterior related;
gut-lung axis;
pulmonary fibrosis;
gut microbiota;
TCM therapy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(11):19-23
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary fibrosis is a respiratory system disorder characterized by damage to alveolar epithelial cells,pathological proliferation and transformation of fibroblasts,excessive deposition of extracellular matrix,leading to structural damage and loss of function in lung tissues,with a high mortality rate and limited effective treatment methods.This article was based on the TCM understanding of"lung connecting to large intestine",namely the theory of"lung and the large intestine being interior-exterior related",and set the modern medical understanding of"lung connecting to large intestine",namely the theory of"gut-lung axis"as the key.Combining the TCM pathogenesis of pulmonary fibrosis and the related mechanisms of"gut-lung axis"in pulmonary fibrosis,it preliminarily expounded the connotation of TCM regulating the"gut-lung axis"to treat pulmonary fibrosis,aiming to provide new ideas for clinical treatment of pulmonary fibrosis through the"gut-lung axis".
