Research Progress in Intervention of Chinese Materia Medica in Th17/Treg Balance in the Treatment of Ulcerative Colitis
10.19879/j.cnki.1005-5304.202310100
- VernacularTitle:中药干预Th17/Treg平衡治疗溃疡性结肠炎研究进展
- Author:
Kaiyang LI
1
;
Mei YANG
;
Jing HUANG
;
Xiaoyuan LIN
;
Jiemin LIU
;
Yun TANG
;
Zhenfan GUO
;
Hui SHI
;
Yueyue YANG
;
Caiyu HUANG
;
Qi ZHAO
Author Information
1. 贵州中医药大学,贵州 贵阳 550002
- Keywords:
ulcerative colitis;
Th17/Treg balance;
mechanism;
Chinese materia medica;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(10):191-196,封3
- CountryChina
- Language:Chinese
-
Abstract:
Pathological mechanism of ulcerative colitis(UC)is not fully clear,which may be the result of Th17/Treg immune imbalance and the interaction of multiple complex factors.Numerous studies have found that classical TCM prescriptions,experienced formulas and TCM active components could regulate Th17/Treg balance by intervening in cytokines,transcription factors,and signaling pathways,restore intestinal mucosal immune function,suppress intestinal mucosal inflammatory response,and repair intestinal mucosal barrier damage.Based on the research status of UC,Th17/Treg balance and TCM treatment,this article reviewed the relationship between Th17/Treg balance and UC,and explained the key role of Th17/Treg balance in the occurrence and development of UC.At the same time,the Chinese materia medica targeting to regulate the balance of Th17/Treg in the treatment of UC in recent years was summarized,in order to provide reference for the treatment of UC.
