Research Progress of Baitouweng Decoction and Its Modified Prescription in the Treatment of Ulcerative Colitis
10.19879/j.cnki.1005-5304.202312170
- VernacularTitle:白头翁汤及其加减方治疗溃疡性结肠炎研究进展
- Author:
Sihui QIN
1
;
Yuan WANG
;
Hui LI
;
Jinge MA
;
Guoying LIANG
Author Information
1. 黑龙江中医药大学,黑龙江 哈尔滨 150040
- Keywords:
Baitouweng Decoction;
ulcerative colitis;
signaling pathway;
inflammatory response;
research progress
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(10):186-190
- CountryChina
- Language:Chinese
-
Abstract:
Baitouweng Decoction is a classic prescription commonly used in the treatment of heat-toxin dysentery,with confirmed efficacy in the treatment of ulcerative colitis(UC).Clinical studies have found that Baitouweng Decoction,modified Baitouweng Decoction,combined with other Chinese materia medica or other therapies for UC can improve the clinical symptoms of patients,reduce the lesion activity score under colonoscopy,promote the healing of intestinal mucosal tissue,and also improve the overall efficiency of treatment,and reduce adverse reactions and recurrence rate.Pharmacological studies showed that Baitouweng Decoction may treat UC by regulating the expressions of related inflammatory factors and signaling pathways,regulating immune function,repairing intestinal mucosal barrier,and improving intestinal flora imbalance.This article systematically reviewed the clinical and basic research progress of Baitouweng Decoction in the treatment of UC,in order to provide a basis for relevant research.