Research Progress in TCM Flavonoids for the Treatment of Parkinson Disease
10.19879/j.cnki.1005-5304.202309051
- VernacularTitle:中药黄酮治疗帕金森病基础研究进展
- Author:
Hongrui CHEN
1
;
Xiaojuan XUE
;
Xue LI
;
Tian XIE
;
Yibing CHEN
Author Information
1. 天津中医药大学第二附属医院临床药理中心,天津 300150
- Keywords:
Parkinson disease;
TCM flavonoids;
antioxidant;
iron metabolism;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(9):191-196
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson disease is a common neurodegenerative disease.At present,the main therapeutic drugs have problems such as adverse reactions,lack of targeting,and low bioavailability.The development of new drugs is an important direction for research related to Parkinson disease.TCM flavonoids have various pharmacological activities and are widely used in anti-tumor and cardiovascular disease treatment,but there is relatively little research on their intervention in neurological diseases.This article elaborated on the mechanism of intervention of TCM flavonoids in Parkinson disease and summarized treatment strategies from six categories:flavonoids,flavonols,isoflavones,flavonoid glycosides,dihydroflavonols,and others,with the purpose to provide reference for the research and clinical application of TCM flavonoids.
