Exploration on the Medication Law of Zhang Binghou in Treating Diabetic Kidney Disease Based on Data Mining
10.19879/j.cnki.1005-5304.202309549
- VernacularTitle:基于数据挖掘探讨张炳厚治疗糖尿病肾病用药规律
- Author:
Mengyu LI
1
;
Haitao SHANG
;
Shiwen ZHANG
;
Wenjing ZHAO
;
Zhen CAI
;
Xinxin PANG
;
Xiaodan YIN
Author Information
1. 河南中医药大学第二临床医学院,河南 郑州 450046
- Keywords:
TCM Inheritance Platform System;
Zhang Binghou;
diabetic kidney disease;
data mining;
medication law
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(9):58-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze Professor Zhang Binghou's medication experience in the treatment of diabetic kidney disease using data mining methods;To screen the core medicinal pairs and medicinal groups.Methods Prescriptions of diabetic kidney disease of Professor Zhang Binghou from the outpatient department of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University were selected from January 2014 to December 2021.TCM Inheritance Platform System 2.5,SPSS Modeler 18 and SPSS Statistics 21 software were used for association rules,clustering analysis and factor analysis to summarize the medication frequency,properties and tastes and meridians,and medicinal pairs and combinations.Results A total of 161 prescriptions were included,involving 188 kinds of Chinese materia medica,with a total frequency of 2 220 time.The kinds of Chinese materia medica with higher frequency were Rehmannize Radix et Praeparata,Testudinis Carapax et Plastrum,Astragali Radix,Rehmannine Radix,etc.The main properties were cold and warm,the main tastes were sweet and bitter,and the main meridians were kidney,liver and spleen meridians.A total of 14 drug pair association rules were obtained,with 27 commonly used drug combinations.Clustering analysis extracted 10 combinations based on the spectrum,and factor analysis extracted 14 common factors.Conclusion Professor Zhang Binghou's treatment for diabetic kidney disease takes nourishing the true yin and clearing away damp-heat as the main treatment method,and at the same time,it pays attention to tonifying kidney,consolidating essence,nourishing yin and containing yang,promoting blood circulation and removing blood stasis,etc.,which embodies Professor Zhang Binghou's unique academic thought of treating diabetic kidney disease.
