Exploration on Targeted Pulmonary Vascular Remodeling for the Treatment of Pulmonary Hypertension Based on Collateral Disease Theory
10.19879/j.cnki.1005-5304.202308465
- VernacularTitle:基于络病理论探讨靶向肺血管重塑治疗肺动脉高压
- Author:
Xianya CAO
1
,
2
;
Junlan TAN
;
Runxiu ZHENG
;
Jian YI
;
Guoran PENG
;
Rongzhen DING
;
Xia LI
;
Feiying WANG
;
Aiguo DAI
Author Information
1. 湖南中医药大学中西医结合学院,湖南 长沙 410208
2. 血管生物学与转化医学湖南省重点实验室,湖南 长沙 410208
- Keywords:
pulmonary hypertension;
collateral disease theory;
pulmonary vascular remodeling;
theoretical exploration
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(9):18-23
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary hypertension(PH)is a progressive pulmonary vascular disease that can lead to right heart failure and death.In recent years,the incidence of PH has been increasing year by year and there is a lack of effective treatment.TCM can play an important synergistic role in the treatment of PH.Pulmonary vascular remodeling is a core pathological feature of PH,which is closely related to the physiological structure and pathological changes of the collaterals.Based on the collateral disease theory,this article described the key pathogenesis of PH in TCM and Western medicine,including the lesions of the pulmonary and cardiovascular complexes and pulmonary vascular remodeling,analyzed the physiology of the"collateral-vessel"in PH,sorting out the pathological correlation,and explored TCM targeting pulmonary vascular remodeling in the identification and treatment of PH,so as to provide a new way of thinking for the clinical treatment of PH.
