Exploration on the Biological Connotation of the Pathogenesis of "Earth Congestion and Wood Depression" of Atherosclerosis from "Intestinal Flora-Bile Acids" Pathway
10.19879/j.cnki.1005-5304.202309200
- VernacularTitle:基于"肠道菌群-胆汁酸"途径探讨动脉粥样硬化"土壅木郁"病机的生物学内涵
- Author:
Haoxian MENG
1
;
Hua JIN
;
Jinmeng XI
;
Yanhu HE
;
Meilong SI
;
Luliang YE
;
Tiantian HOU
Author Information
1. 甘肃中医药大学中医临床学院,甘肃 兰州 730000
- Keywords:
atherosclerosis;
bile acids;
intestinal flora;
earth congestion and wood depression
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(9):12-17
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal flora and bile acid metabolism regulate and influence each other,and an imbalance in the"intestinal flora-bile acid"pathway is closely related to atherosclerosis.Based on TCM theory and clinical practice,it is found that"earth congestion and wood depression"is the key mechanism of atherosclerosis,but its biological connotation needs to be further elucidated.Combined with the results of modern research,it is believed that intestinal flora imbalance is an important foundation of"earth congestion",and bile acid metabolism abnormality is an important manifestation of"wood depression".In the process of atherosclerosis,the imbalance of the"intestinal flora-bile acid"pathway is closely related to the"earth congestion and wood depression"pathogenesis of TCM in atherosclerosis.Exploring the biological connotation of the pathogenesis of"earth congestion and wood depression"of atherosclerosis from the"intestinal flora-bile acids"pathway is of far-reaching significance for clarifying the scientific connotation of TCM theory and guiding the TCM prevention and treatment of atherosclerosis.
