Visualization Analysis of Research on the TCM Regulation of Cellular Autophagy
10.19879/j.cnki.1005-5304.202307049
- VernacularTitle:中医药调控细胞自噬研究文献可视化分析
- Author:
Dan LONG
1
;
Chenhan MAO
;
Yaxuan LIU
;
Junjun ZOU
;
Yin XU
;
Ying ZHU
Author Information
1. 湖南中医药大学第一附属医院,湖南 长沙 410021
- Keywords:
TCM;
autophagy;
knowledge graph;
bibliometrics;
CiteSpace;
VOSviewer
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(7):50-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the current status,hotspots and trends of research on the TCM regulation of cellular autophagy;To provide reference for related research.Methods The literature related to the TCM regulation of cellular autophagy was retrieved from CNKI,Wanfang Data,VIP and CBM from the establishment of the databases to December 31,2022.Authors and institutional collaboration networks were drawn using CiteSpace 5.7.R5.keywords emergence analysis and timeline view were drawn.VOSviewer 1.6.18 software was used to draw keyword co-occurrence mapping.Results A total of 2 001 articles were included,with a general upward trend in the number of publications.The cooperation teams were mainly represented by Jia Lianqun,Yang Guanlin,Song Nan and others.Research institutions with more publications included Hunan University of Chinese Medicine,Liaoning University of Chinese Medicine,and Guangzhou University of Chinese Medicine.The keywords of the literature formed 9 meaningful clusters,showing that the research hotspots in this field mainly focused on apoptosis,mitochondrial autophagy,experimental studies,signaling pathways,and herbal monomers,etc.TCM interventions that attracted much attention included electroacupuncture,moxibustion,resveratrol,curcumin,etc,mainly involving PI3K/Akt,AMPK/mTOR and other signaling pathways.Conclusion The research on cellular autophagy in the field of TCM has been highly popular in recent years.Experimental studies,molecular mechanisms,related diseases,and TCM intervention are the research hotspots in this field.The research trend is dominated by TCM monomer,TCM theory research and other directions,mainly focusing on apoptosis,oxidative stress and other pathways to carry out extensive research.
