Progress in comprehensive therapy for advanced gastric cancer
10.12354/j.issn.1000-8179.2024.20240679
- VernacularTitle:晚期胃癌的综合治疗进展
- Author:
Gao HONGCHAO
1
;
Peng ZHI
Author Information
1. 北京大学肿瘤医院暨北京市肿瘤防治研究所消化肿瘤内科,消化系统肿瘤整合防治全国重点实验室,恶性肿瘤转化研究北京市重点实验室(北京市 100142)
- Keywords:
advanced gastric cancer;
comprehensive therapy;
conversion therapy;
local therapy;
multidisciplinary therapy
- From:
Chinese Journal of Clinical Oncology
2024;51(17):896-901
- CountryChina
- Language:Chinese
-
Abstract:
In China,most patients with gastric cancer are diagnosed at an advanced stage,making comprehensive treatment for advanced gastric cancer crucial.Systemic pharmacotherapy is the mainstay treatment for such patients.Guided by the concept of precision medicine,trastuzumab deruxtecan for HER2-positive patients and immunotherapy,such as nivolumab in combination with chemotherapy,have signi-ficantly improved the survival outcomes of patients with advanced gastric cancer.Furthermore,local therapy,nutritional support,and psychosocial interventions have enhanced patient quality of life.Herein,the perioperative treatment strategies,feasibility of reduced lymph-adenectomy,and surgery-sparing approaches are explored,emphasizing the importance of a multidisciplinary treatment models to achieve individualized and precise treatment for patients with advanced gastric cancer.
