Potential and efficacy of adaptive immunotherapy radiotherapy for non-small cell lung cancer
10.12354/j.issn.1000-8179.2024.20240712
- VernacularTitle:适应性免疫放疗非小细胞肺癌的潜力与疗效
- Author:
Yao ZHUORAN
1
;
Luo REN
;
Kang KAI
;
Xue JIANXIN
;
Lu YOU
Author Information
1. 四川大学华西医院肿瘤中心胸部肿瘤病房,肿瘤中心放疗科(成都市 618099)
- Keywords:
non-small cell lung cancer(NSCLC);
immunotherapy;
radiotherapy;
adaptive immunotherapy radiotherapy(AIRT)
- From:
Chinese Journal of Clinical Oncology
2024;51(16):829-834
- CountryChina
- Language:Chinese
-
Abstract:
Immune checkpoint inhibitor(ICI)-based combination therapies have achieved great breakthroughs in the treatment of advanced non-small cell lung cancer(NSCLC)with negative driver genes;however,challenges persist owing to unmet clinical needs.Recent advances in fundamental and translational research on radioimmunotherapy offer hope for addressing these challenges.Adaptive immunotherapy ra-diotherapy(AIRT)is a promising treatment modality with potential applicability and universality that can provide accessibility and potentially superior clinical outcomes to most patients undergoing chemoimmunotherapy.However,extensive fundamental research and clinical trials in radiation oncology is required to substantiate the efficacy of this approach.
