Trends of Incidence and Age at Onset of Female Breast Cancer in Jiangsu Cancer Registration Areas from 2009 to 2019
10.11735/j.issn.1004-0242.2024.12.A002
- VernacularTitle:2009-2019年江苏省肿瘤登记地区女性乳腺癌发病趋势及年龄变化分析
- Author:
Yingying HAN
1
;
Bo CAI
;
Ling LIN
;
Jinyi ZHOU
;
Ran TAO
;
Weigang MIAO
;
Renqiang HAN
Author Information
1. 南通市疾病预防控制中心,江苏南通 226007
- Keywords:
cancer registry;
female breast cancer;
incidence rate;
age;
trend;
Jiangsu
- From:
China Cancer
2024;33(12):970-976
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To investigate the trends of incidence and age at onset of female breast can-cer in Jiangsu cancer registration areas from 2009 to 2019.[Methods]The continuous monitoring data of female breast cancer from 2009 to 2019 were collected from 16 cancer registries in Jiangsu Province.All datasets were checked and evaluated based on data quality control criteria and were included in the analysis.Crude rate(CR),age-standardized incidence rate by Chinese standard population(ASIRC),the average annual percentage change(AAPC),crude and adjusted mean age at onset were calculated.Incidence rates stratified by regions and age groups were calculated.Age-period-cohort model was used to analyze the changes of cancer incidence and age-adjusted mean ages.[Results]The incidence CR of female breast cancer was significantly increased from 24.39/105 in 2009 to 46.72/105 in 2019 with an AAPC in CR of 6.97％(95％CI:5.26％～8.70％)and AAPC in ASIRC of 4.67％(95％CI:3.00％～6.37％).The crude mean age and adjusted mean age at onset increased from 54.10 and 52.89 years old in 2009 to 56.23 and 53.36 years old in 2019,respectively.Crude mean age at onset increased significantly over time in all registry areas(β=0.21,P＜0.001),urban(β=0.1 8,P＜0.001)and rural(β=0.25,P＜0.001)areas,while adjusted mean age at onset remained stable in all registry areas(β=0.05,P=0.024)and rural areas(β=0.09,P=0.008).From 2009 to 2019,the incidence rate of female breast cancer of all age groups showed upward trends,with an average annual growth rate of 3.26％to 7.79％(all P＜0.05),and the incidence rate in rural areas increased faster than that in urban areas.The age composition of breast cancer onset and standardized age composition of onset in women over 60 years old showed an upward trend(all P＜0.05).[Conclusion]The incidence rate of female breast cancer in Jiangsu Province in-creased from 2009 to 2019,and the mean age of onset showed a backward trend.
