One case of anti synthetase antibody syndrome characterized by interstitial lung disease
10.3760/cma.j.cn101721-20240419-00125
- VernacularTitle:以间质性肺疾病为主要特征的抗合成酶抗体综合征1例
- Author:
Yushan ZHANG
1
;
Yingying XU
;
Zhengfan YU
;
Leqiang WANG
Author Information
1. 山东第二医科大学第一附属医院 潍坊市人民医院，潍坊 261000
- Keywords:
Interstitial lung disease;
Anti-synthetic enzyme antibody;
Anti-synthetase syndrome;
Jo-1 antibody;
Anti-Ro52
- From:
Clinical Medicine of China
2024;40(5):375-378
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To strengthen the understanding of clinical features, chest imaging changes and myositis markers of interstitial lung disease associated with anti-synthase syndrome, and to broaden clinical thinking for the diagnosis and treatment of lung disease.Methods:Analyze the clinical diagnosis and treatment process of a patient with anti synthetase antibody syndrome who was admitted to Weifang People's Hospital on March 12, 2023, and summarize the literature.Results:The patient complained of coughing, chest tightness, and shortness of breath for more than 2 months. The initial diagnosis upon admission is community-acquired pneumonia and interstitial pneumonia. After admission, complete relevant auxiliary examinations, supplement the diagnosis of anti synthetase antibody syndrome, and provide standardized treatment Afterwards, the patient's clinical symptoms such as chest tightness and cough were completely relieved, and a follow-up chest CT scan showed a significant reduction in the size of the lesion.Conclusion:For patients with unexplained interstitial pneumonia, it is necessary to actively broaden the diagnosis and treatment thinking, especially considering the possibility of some rheumatic and immune diseases complicated with interstitial lung disease.
