dMRI based on various theories of brain microstructure and the application of that in the research for PD
10.3969/j.issn.1672-8270.2024.09.029
- VernacularTitle:基于不同脑微结构理论的扩散磁共振成像在帕金森病研究中的应用
- Author:
Jiaqi TIAN
1
;
Qiping WEN
;
Jiabin LU
;
Xuejiao LI
;
Wei WANG
Author Information
1. 首都医科大学附属北京康复医院放射科 北京 100043
- Keywords:
Parkinson's disease(PD);
Diffusion kurtosis imaging(DKI);
Neurite orientation dispersion and density imaging(NODDI);
Diffusion tensor imaging index of perivascular space(DTI-ALPS)
- From:
China Medical Equipment
2024;21(9):155-161
- CountryChina
- Language:Chinese
-
Abstract:
The diagnosis of Parkinson's disease(PD)mainly relies on clinical appearance of patients,and the routine magnetic resonance scan has difficulty in finding the abnormality of that,which is not able to meet the requirement of early and precise quantification for the PD lesion area.Diffusion magnetic resonance imaging(dMRI)technique is a noninvasive method of examining the microstructure of living tissue.Diffusion weighted imaging(DWI)and diffusion tensor imaging(DTI)were the most widely used in clinical practice.However,the principles of them have limitation,which are not able to fully outline the microstructure of brain tissue.This paper discussed several new dMRI techniques that are able to make up conventional dMRI model,which included diffusion kurtosis imaging(DKI),neurite orientation dispersion and density imaging(NODDI)and diffusion tensor imaging index of perivascular space(DTI-ALPS).Moreover,this paper summarized the applications of above imaging technique in exploring the changes of the microstructure of brain tissue of PD patients,so as to provide more imaging information for the pathological changes of PD patients.
