Rapid health technology assessment Meta-analysis of drug-eluting coronary stent system for the treatment of coronary heart disease
10.3969/j.issn.1672-8270.2024.07.021
- VernacularTitle:可吸收药物洗脱冠状动脉支架系统治疗冠心病的快速卫生技术评估Meta分析
- Author:
Dandan ZHU
1
;
Huilin XIA
;
Yali JIANG
;
Bin ZHOU
;
Jianchao JIA
;
Xiaoyan ZHANG
;
Yuefei LI
Author Information
1. 内蒙古自治区人民医院医学工程处 呼和浩特 010017
- Keywords:
Absorbable drug-eluting coronary stent;
Drug-eluting coronary stent;
Coronary artery disease;
Rapid health technology assessment;
Meta analysis
- From:
China Medical Equipment
2024;21(7):116-121,127
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effectiveness,safety and economics of absorbable drug-eluting coronary stent systems using rapid health technology assessment tools,and to provide evidence-based basis for rational use for clinicians use and expert evaluation.Methods:A computer search was performed on PubMed,CNKI,Wanfang,VIP and other databases from 1 January 2014 to 1 January 2023 for relevant literature on patients with coronary artery disease who were treated with coronary artery stent interventional surgery.The 210 collected literatures were screened and extracted according to the inclusion and exclusion criteria,and the literature quality evaluation was carried out.The extracted data related to the intravascular thrombosis rate,myocardial infarction rate,cardiac mortality rate,all-cause mortality rate,target lesion revascularization rate and intravascular adverse event incidence of absorbable drug-eluting coronary stents and drug-eluting coronary stents were meta-analyzed by Revman5.4 software.Results:7 studies were ultimately included in the comparative study of absorbable drug-eluting coronary stents and drug-eluting coronary stents.The thrombosis rate,all-cause mortality rate and intravascular adverse event rate of absorbable drug-eluting coronary stents were lower than those of drug-eluting coronary stents,and the difference was statistically significant(Z=2.16,1.89,2.22,P＜0.05).There were no statistically significant difference in the myocardial infarction rate,cardiac mortality rate and target lesion revascularization rate between absorbable drug-eluting coronary stents and drug-eluting coronary stents(P＞0.05).Conclusion:There was no significant difference in safety and efficacy between absorbable drug-eluting coronary stents and drug-eluting coronary stents.In terms of economy,the cost of absorbable drug-eluting coronary stents is significantly higher than that of drug-eluting coronary stents,and patients can choose stents according to their own economic conditions and other actual conditions.
