Application of Enhanced T2* Weighted Angiography Quantitative Parameters in Predicting the Invasiveness of Cystic Gland Tumors
10.3969/j.issn.1005-5185.2024.11.012
- VernacularTitle:增强T2*加权血管成像定量参数在预测卵巢囊腺肿瘤侵袭性中的应用价值
- Author:
Jing WANG
1
;
Jiejun ZHANG
;
Jinbao YU
Author Information
1. 安徽省宣城市中心医院影像科,安徽 宣城 242000
- Keywords:
Magnetic resonance imaging;
Angiography;
Cystadenoma;
Ovarian neoplasms;
Invasiveness;
R2* value
- From:
Chinese Journal of Medical Imaging
2024;32(11):1160-1163,1169
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To analyze the application value of enhanced T2* weighted angiography(ESWAN)quantitative parameters in predicting the invasiveness of cystic gland tumors.Materials and Methods A total of 81 patients with ovarian cystadenoma confirmed by pathological examination in Central Hospital of Xuancheng City,Anhui Province from June 2018 to June 2023 were retrospective selected.All patients underwent pelvic MRI examination(including ESWAN sequence).The ESWAN data was processed to obtain amplitude,phase,R2* and T2*values,and the quantitative intratumoral susceptibility signal(ITSS)ratio was automatically obtained using AnatomySketch software.According to the invasiveness of ovarian cystic gland tumors,they were divided into malignant cystic gland tumor group and benign cystic gland tumor group(including benign and borderline cystic gland tumors).The differences in various parameters between the two groups were compared,and the receiver operating curve was used to evaluate the predictive efficacy of each parameter on the invasiveness of ovarian cystic gland tumors.Results Among the 81 patients with ovarian cystic tumors,29 patients were in the malignant cystic tumor group,with an incidence rate of 35.80%.The CA-125,R2* values and ITSS ratio in the malignant cystic gland tumor group were higher than those in the benign cystic gland tumor group,and the differences were statistically significant(t=15.153,14.006,8.200,all P<0.05).The R2* value(OR=3.464,95%CI 1.712-7.008,P=0.001)and ITSS ratio(OR=8.376,95%CI 1.399-14.519,P=0.002)were independent risk factors for the occurrence of malignant ovarian cystadenoma(OR>1,P<0.05);the optimal critical values for R2* value,ITSS ratio and their combined prediction of malignant ovarian cystic tumors were 5.700,0.165 and 0.557,respectively.The area under the curve was 0.942,0.870 and 0.975,respectively.The sensitivity was 82.80%,82.80%and 89.70%,and the specificity was 96.20%,75.00%and 98.10%.Conclusion R2* value and ITSS ratio are independent predictive molecules for malignant cystic tumors,and their combination can enhance the predictive efficacy of invasiveness in ovarian cystic tumors.
