Spleen Stiffness in Predicting High Risk Esophageal and Gastric Varices in Cirrhosis via Shear Wave Elastography
10.3969/j.issn.1005-5185.2024.11.011
- VernacularTitle:剪切波弹性成像测量脾脏硬度预测肝硬化高风险食管胃底静脉曲张
- Author:
Kai YANG
1
;
Ruiling HE
;
Sumei MA
;
Xiaorong MAO
Author Information
1. 兰州大学第一临床医学院,甘肃 兰州 730000
- Keywords:
Liver;
Spleen;
Shear-wave elastography;
Cirrhosis;
Esophageal and gastric varices;
Ultrasonography
- From:
Chinese Journal of Medical Imaging
2024;32(11):1155-1159
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the value of shear wave elastic imaging of liver and spleen in predicting high risk esophageal and gastric varices in cirrhosis.Materials and Methods Sixty-four patients with cirrhosis in the First Hospital of Lanzhou University from November 2019 to April 2022 were enrolled prospectively,and underwent gastroscopy,elastography and serological examination.According to gastroscopy,patients were divided into high-risk varices(HRV,30 cases)and non-HRV group(34 cases),the differences of each clinical index and shear wave elastic imaging parameter between the groups were compared.The diagnostic efficacy of liver and spleen stiffness measurement for HRV was analyzed.And the diagnostic models were established for exploring the diagnostic effectiveness of different models with respect to excluding HRV in compensated liver cirrhosis.Results There were significant differences in platelet[(74±24)×109/L vs.(124±50)×109/L],liver stiffness[(16.1±5.6)kPa vs.(13.6±5.5)kPa]and spleen stiffness[(41.7±8.9)kPa vs.(28.1±8.6)kPa]between HRV and non-HRV groups(t/Z/χ2=5.136,-1.832,-6.206,all P<0.05).The areas under the curve of liver stiffness and spleen stiffness for predicting HRV were 0.660 and 0.858,respectively.The Baveno Ⅵ combined with the spleen stiffness model had the best performance(30.0％)for excluding HRV.Conclusion The measurement of liver and spleen stiffness by shear wave elastography has great diagnostic value for predicting HRV in cirrhosis,and spleen stiffness is better than liver stiffness.
