Neonatal Cholestasis Associated with Congenital Hypopituitarism.
- Author:
Hye Ran YANG
1
;
Eun Gyoung SONG
;
Jeong Eun KIM
;
Su Jin JEONG
;
Gyoung Hoon LEE
;
Choong Ho SHIN
;
Sei Won YANG
;
Jae Sung KO
;
Gyeong Hoon KANG
;
Jeong Kee SEO
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. jkseo@plaza.snu.ac.kr
- Publication Type:Case Report
- Keywords:
Neonatal cholestasis;
Hypopituitarism;
Hypoglycemia
- MeSH:
Bile;
Cholestasis*;
Hydrocortisone;
Hypoglycemia;
Hypopituitarism*;
Thyroxine
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2002;5(2):199-205
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Congenital hypopituitarism is a possible cause of neonatal cholestasis, but the mechanism is still unknown. The pathogenesis of cholestasis may be due to hormone deficiency, which has effects on the physiological maturation of bile acid synthesis and transport. We experienced a case presenting with cholestasis and recurrent hypoglycemia associated with congenital hypopituitarism. Cholestasis resolved with thyroxine and hydrocortisone replacement therapy