Feasibility and Protocol Selection of Virtual Non-Contrast Technology Replacing True Non-Contrast Scanning in Tri-Phase of Liver Lesions with Spectral CT
10.3969/j.issn.1005-5185.2024.08.010
- VernacularTitle:肝脏占位病变能谱CT成像中不同期相虚拟平扫替代真实平扫的效能及方案选择
- Author:
Fangyan GU
1
;
Xiaomei ZHU
;
Fang NIE
;
Wei WANG
Author Information
1. 东南大学附属中大医院放射科,江苏 南京 210009
- Keywords:
Tomography,X-ray computed;
Liver diseases;
Virtual non-contrast;
Feasibility analysis
- From:
Chinese Journal of Medical Imaging
2024;32(8):809-815
- CountryChina
- Language:Chinese
-
Abstract:
Purpose Based on liver lesions,to investigate the feasibility and influencing factors of virtual non-contrast(VNC)replacing true non-contrast(TNC)in tri-phase derived from Revolution CT.Materials and Methods A total of 62 patients who underwent TNC and tri-phase(arterial,venous,and delayed phases)spectral enhanced liver scans were retrospectively enrolled in Zhongda Hospital Affiliated to Southeast University from December 2021 to April 2022.Liver lesions with a diameter of≥5 mm were measured and categorized into Group 1(≤20 Hu)and Group 2(>20 Hu)according to the CT values of TNC,then were respectively further categorized into group a(≤20 Hu across all three phases of enhancement)and group b(>20 Hu in at least one phase of enhancement)based on the degree of enhancement.CT attenuation,maximum diameter and detection rates of lesions were compared between TNC and three-phase VNC groups.Multivariate regression analysis was used to investigate the influencing factors of the density difference between VNC and TNC.Results A statistically significant difference in the attenuation of lesions was observed among the each groups(χ2/F=14.712,18.603,7.334,all P<0.01).Except for VNCV and VNCD in Group-1a which had no significant difference with TNC(both P>0.05),the attenuation of other VNCs were lower than TNC in category-a and greater than TNC in category-b(all P<0.05).Maximal diameter presented strong correlation and no significant difference in VNCA and VNCV compared to TNC in each group(all P>0.05;all r>0.8 and P<0.001).A significant difference in the detection rate of the lesions was observed among the groups(χ2=47.660,P<0.001),VNCV images displayed the higher detection rate than VNCA and VNCD(all P<0.05).The density difference between VNC and TNC was positively correlated with CT values of the corresponding enhancement phase(r2adjusted=0.209,0.142,0.062,P<0.001).Conclusion Based on Revolution CT,VNCV is the optimal phase to replace TNC and can be mitigated by CT value of the lesions in venous-phase.
