Influence of Spin-Lock Frequency on Quantitative Assessment of Myocardial T1ρ Mapping
10.3969/j.issn.1005-5185.2024.07.018
- VernacularTitle:自旋锁定频率对心肌定量T1ρ成像的影响
- Author:
Caiyun HAN
1
;
Wei DENG
;
Ren ZHAO
;
Hongmin SHU
;
Zhen WANG
;
Jinxiu YANG
;
Yongqiang YU
;
Xiaohu LI
Author Information
1. 安徽医科大学第一附属医院医学影像科,安徽 合肥 230022
- Keywords:
Myocardium;
Myocardial fibrosis;
Magnetic resonance imaging;
T1ρ mapping;
Spin-lock frequency
- From:
Chinese Journal of Medical Imaging
2024;32(7):731-735
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To explore the influence of different spin-locking frequencies on T1ρ values based on a 3.0T MR system.Materials and Methods Thirty-eight healthy adult volunteers underwent cardiac magnetic resonance imaging at the First Affiliated Hospital of Anhui Medical University from July to September 2023.T1ρ mapping and short-axis cine imaging with steady-state free precession sequences were performed with 3.0T MR system.T1ρ mapping sequence in three short-axis slices with three spin-lock frequencies at the amplitude of 5 Hz,300 Hz,400 Hz,and 500 Hz was scanned,respectively.T1ρ relaxation times and myocardial fibrosis index were quantified for each slice and each myocardial segment,the difference in T1ρ of different spin-locking frequencies and myocardial fibrosis index was analyzed using one-way repeated-measures analysis of variance method.Results T1ρ of 5 Hz,300 Hz,400 Hz,and 500 Hz were(33.9±2.8)ms,(43.4±2.1)ms,(45.4±2.6)ms and(46.5±2.4)ms,respectively;and T1ρ values showed a significant progressive increase from the low spin-lock frequency to the high spin-lock frequency of the heart(300 Hz vs.400 Hz:P<0.001;300 Hz vs.500 Hz:P<0.001;400 Hz vs.500 Hz:P=0.043).In addition,the measured myocardial fibrosis index at 300 Hz,400 Hz and 500 Hz were(9.4±2.2)ms,(11.3±2.9)ms and(12.6±2.7)ms,respectively.Statistical analysis underscored significant variations among these measurements(300 Hz vs.400 Hz:P<0.001;300 Hz vs.500 Hz:P<0.001;400 Hz vs.500 Hz:P=0.033).Conclusion In this prospective study,myocardial T1ρ values for the specific cardiac magnetic resonance setting are provided,and we found that spin-lock frequency can affect the T1ρ values.
