Dual-source CT virtual monoenergetic imaging for differentiating prostate cancer and benign prostatic hyperplasia
10.13929/j.issn.1003-3289.2024.11.024
- VernacularTitle:双源CT虚拟单能量成像鉴别诊断前列腺癌与前列腺增生
- Author:
Xinwei ZHONG
1
;
Yi CHEN
;
Bowen YUE
;
Jianhui LI
;
Hao ZHANG
;
Xiaohong CHEN
;
Xiaofeng CHEN
;
Junliang DENG
;
Wenzhong HOU
;
Zhiqi YANG
Author Information
1. 汕头大学医学院梅州临床学院梅州市人民医院放射科,广东梅州 514031
- Keywords:
prostatic neoplasms;
prostatic hyperplasia;
tomography,X-ray computed;
diagnosis,differential
- From:
Chinese Journal of Medical Imaging Technology
2024;40(11):1749-1753
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of dual-source CT(DECT)virtual monoenergetic imaging(VMI)for differentiating prostate cancer(PC)and benign prostatic hyperplasia(BPH).Methods Thirty-three patients with PC(PC group)and 44 patients with BPH(BPH group)were retrospectively enrolled,and 40-100 keV(with 10 keV interval)VMI were reconstructed based on arterial phase DECT images,respectively.Clinical data,focal CT value and contrast-to-noise ratio(CNR)of VMI with different energy levels and conventional linear fusion images of arterial phase were compared between groups.Binary logistic regression models were constructed based on clinical data being significantly different between groups,focal CT value of VMI with energy level with the highest CNR,also focal CT value of conventional linear fusion images of arterial phase,respectively.The area under the receiver operating characteristic curve(AUC)was calculated to evaluate the efficacy of each model for differentiating PC and BPH.Results Free prostate-specific antigen(f-PSA),total prostate-specific antigen(t-PSA),focal CT value of 40-100 keV VMI and conventional linear fusion images of arterial phase in PC group were all higher,while short diameter in PC group was smaller than those in BPH group(all P＜0.05).Logistic regression models were constructed based on f-PSA,t-PSA,short diameter,CT value at 40 keV VMI and CT value at conventional linear fusion images of arterial phase,respectively,with AUC for differentiating PC and BPH of 0.879,0.902,0.701,0.911 and 0.857,respectively.Conclusion DECT VMI could be used as a supplementary examination for prostate diseases,and 40 keV VMI had the best efficacy for differentiating PC and BPH.
