Spectral CT quantitative parameters for evaluating T stage of advanced gastric cancer
10.13929/j.issn.1003-3289.2024.11.015
- VernacularTitle:能谱CT定量参数评估进展期胃癌T分期
- Author:
Yaru YOU
1
;
Yiyang LIU
;
Mengchen YUAN
;
Shuai ZHAO
;
Liming LI
;
Yusong CHEN
;
Yue ZHENG
;
Jianbo GAO
Author Information
1. 郑州大学第一附属医院放射科,河南郑州 450052
- Keywords:
stomach neoplasms;
neoplasm staging;
tomography,X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2024;40(11):1704-1709
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of spectral CT parameters for evaluating T staging of advanced gastric cancer(AGC).Methods Totally 155 AGC patients were collected and divided into T2 stage(n=40)and T3/4a stage(n=115)according to postoperative pathology.CT values,water concentration(WC)and iodine concentration(IC)of AGC lesions on 40-140 keV arteriovenous phase single energy level images were measured,and the standardized IC(nIC)and spectral curve slopes k1 and k2 were calculated.Clinical variables and spectral quantitative parameters were compared between groups,and receiver operating characteristic curve was plotted,the area under the curve(AUC)was calculated to evaluate the value of each parameter and model for identifying T2 and T3/4a stage AGC.Results Tumor thickness,proportion of low differentiation degree,CT100kev,CT140kev,and WC values in T3/4a group were all significantly higher than those in T2 group(all P＜0.05).CT140keV of AGC lesions on venous phase images presented the highest discrimination efficacy among single parameters,with AUC of 0.782.AUC of clinical-arterial phase-venous phase model was 0.848,higher than that of clinical model and arterial phase model alone(both P＜0.05)but not significantly different compared with AUC of venous phase model(P＞0.05).Conclusion Spectral CT quantitative parameters,especially venous phase parameters could be used to effectively identify T stage of AGC.Multi-parameter combined models had higher diagnostic value.
