Contrast-enhancement mammography for differentiating benign and malignant breast lesions with calcifications
10.13929/j.issn.1003-3289.2024.11.012
- VernacularTitle:对比增强乳腺摄影鉴别乳腺良、恶性钙化性病变
- Author:
Jun CHEN
1
;
Xuan YUAN
;
Yue LI
;
Guang YANG
;
Bei HUA
;
Jindan GE
;
Dandan ZHAO
Author Information
1. 河北医科大学第四医院放射科,河北石家庄 050011
- Keywords:
breast neoplasms;
calcinosis;
mammography;
contrast media
- From:
Chinese Journal of Medical Imaging Technology
2024;40(11):1688-1692
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of contrast-enhanced mammography(CEM)for differentiating benign and malignant breast lesions with calcifications.Methods Data of 116 female patients with 132 breast imaging reporting and data system(BI-RADS)category 4 to 5 lesions were retrospectively analyzed.The lesions were divided into malignant group(n=86)and benign group(n=46)according to the pathologic results.The morphological manifestations of calcification and their distributions were classified into high or low risk,and the combined risk typing of calcifications was assessed according to these two.Finally,an overall risk typing of CEM was obtained through combining the combined risk type of calcifications and accompanied enhancement or not.Then receiver operating characteristic(ROC)curves were drawn,the area under the curves(AUC)were calculated,and the efficacy of the above indexes for differentiating benign and malignant breast lesions with calcifications were evaluated and compared.Results Significant differences of morphology,distribution and accompanied enhancement were found between groups(all P＜0.05).The AUC of morphology risk,distribution risk,the combined risk of calcification,accompanied enhancement and CEM overall risk for differentiating benign and malignant breast lesions with calcifications was 0.709,0.678,0.774,0.800 and 0.875,respectively,of CEM overall risk was higher than that of the others(all P＜0.05).Conclusion CEM overall risk type obtained through integrating morphology and distribution manifestations of calcifications and enhancement type could improve the efficiency of CEM for differentiating benign and malignant breast lesions with calcifications.
