Pseudo-continuous arterial spin labeling MRI for evaluating renal function in patients with renal occupying lesions
10.13929/j.issn.1003-3289.2024.10.021
- VernacularTitle:伪连续式动脉自旋标记MRI评估肾脏占位患者肾功能
- Author:
Liting ZHONG
1
,
2
,
3
;
Ruixiong YOU
;
Shiqian LIN
;
Qi CHEN
Author Information
1. 福建医科大学附属第一医院医学影像科,福建 福州 350004
2. 福建医科大学附属第一医院滨海院区国家区域医疗中心医学影像科,福建 福州 350200
3. 中国人民解放军陆军第七十三集团军医院医学影像科,福建厦门 361000
- Keywords:
kidney neoplasms;
renal insufficiency;
magnetic resonance imaging;
arterial spin labeling
- From:
Chinese Journal of Medical Imaging Technology
2024;40(10):1557-1561
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of pseudo-continuous arterial spin labeling(PCASL)MRI for evaluating renal function in patients with renal occupying lesions.Methods Totally 56 patients with single renal occupying lesion were retrospectively enrolled.The left and right side kidneys were divided into normal renal function group(normal group,30 ml/min)and damaged renal function group(damaged group,＜30 ml/min)according to glomerular filtration rate(GFR)measured with 99Tcm-DTPA dynamic renal imaging,respectively.The total renal blood flow(tRBF)and cortical renal blood flow(cRBF)were calculated using total nephrometry and cortical nephrometry based on PCASL MRI,respectively,then GFR,tRBF and cRBF were compared between groups on the same side.Receiver operating characteristic curve was drawn,and the area under the curve(AUC)was calculated to evaluate the efficacy of tRBF and cRBF for assessing unilateral renal injury.Pearson correlation analysis was performed to observe the correlations of tRBF and cRBF with GFR.Results GFR,tRBF and cRBF in left/right damaged group were all significantly lower than those in ipsilateral normal group(all P＜0.05).AUC of tRBF and cRBF for assessing left renal injury was 0.823 and 0.813,respectively,being not significantly different(P＞0.05).AUC of tRBF and cRBF for assessing right renal injury was 0.940 and 0.922,respectively,being not significantly different(P＞0.05).No obvious correlation of bilateral tRBF nor cRBF with GFR was found(all P＞0.05).Conclusion PCASL MRI could effectively evaluate renal function in patients with renal occupying lesion,and the efficacy of total nephrometry was comparable to that of cortical nephrometry.
