Spectral CT for predicting regional lymph node metastasis of colorectal cancer
10.13929/j.issn.1003-3289.2024.09.019
- VernacularTitle:光谱CT预测结直肠癌区域淋巴结转移
- Author:
Shuiqing ZHUO
1
;
Yadan LIU
;
Linling JIANG
;
Shuwen ZHENG
;
Jin FU
;
Lizhi LIU
Author Information
1. 中山大学肿瘤防治中心影像科华南恶性肿瘤防治全国重点实验室广东省恶性肿瘤临床医学研究中心,广东 广州 510060
- Keywords:
colorectal neoplasms;
lymphatic metastasis;
tomography,X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2024;40(9):1366-1370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of spectral CT for predicting regional lymph node metastasis of colorectal cancer(CRC).Methods Totally 73 patients with CRC confirmed by postoperative pathology were retrospectively enrolled and divided into positive group(n=29)and negative group(n=44)based on the presence or absence of regional lymph node metastasis.The lymph node short diameter,CT value of 120 kV conventional image(CT value120 kV),CT values of 40 keV and 70 keV virtual single energy images(CT value40 keV and CT value70keV),iodine density(ID),effective atomic number(Zeff)and spectral curve slope(λHU).The above parameters and clinical indicators were compared between groups.After excluding those with variance inflation factor greater than 10,model 1 was constructed based on carbohydrate antigen 19-9(CA19-9)and carcinoembryonic antigen(CEA),model 2 based on conventional CT parameters(lymph node short diameter,CT value120 kV),model 3 based on spectral CT parameters(CT value70 keV,ID,Zeff,λHU),and model 4 based on conventional CT parameters and spectral CT parameters.The efficacy of 4 models for predicting regional lymph node metastasis of CRC were analyzed.Results Significant differences in patients'gender,carbohydrate antigen 19-9(CA1 9-9),carcinoembryonic antigen(CEA),lymph node short diameter,CT value120 kV,CT value40 keV,CT value70 keV,ID,Zeff and λHU were found between 2 groups(all P＜0.05).The area under the curve(AUC)of model 1-4 for predicting regional lymph node metastasis of CRC was 0.734,0.752,0.996 and 0.995,respectively,and significant differences were found between model 1 and 3,model 1 and 4,model 2 and 3,as well as model 2 and 4(all P＜0.001).Conclusion Enhanced venous phase spectral CT could effectively predict regional lymph node metastasis of CRC.
