Ultrafast pulse wave velocity technique for evaluating changes of carotid artery elasticity in Hashimoto thyroiditis patients with euthyroidism
10.13929/j.issn.1003-3289.2024.08.014
- VernacularTitle:极速脉搏波技术评估甲状腺功能正常桥本甲状腺炎患者颈动脉弹性改变
- Author:
Yanhui JIANG
1
;
Meiling LIU
;
Jingwen XIE
;
Jianxing ZHANG
Author Information
1. 广州中医药大学第二附属医院超声影像科,广东广州 510120
- Keywords:
Hashimoto disease;
carotid arteries;
ultrasonography;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2024;40(8):1179-1182
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of ultrafast pulse wave velocity(UFPWV)technique for evaluating changes of carotid artery elasticity in Hashimoto thyroiditis(HT)patients with euthyroidism.Methods Conventional ultrasound and UFPWV for carotid artery were prospectively performed in 91 HT patients with euthyroidism(HT group)and 81 healthy subjects(control group).Clinical data and ultrasonic parameters were compared between groups.Spearman correlation analysis was performed to observe the correlations of carotid pulse wave velocity in end of systole(PWV-ES)with clinical indexes and other ultrasonic parameters in HT group.Multiple stepwise linear regression analysis was used to screen the independent impact factors of increased carotid PWV-ES in HT group.Results Significant differences of thyroid peroxidase antibody(TPOAb),thyroglobulin antibody(TgAb),total cholesterol(TC),low density lipoprotein and neutrophil-lymphocyte ratio(NLR)were found between groups(all P＜0.05).The carotid PWV-ES in HT group was significantly higher than that in control group(P＜0.05),while no significant difference of carotid artery intima-media thickness(CIMT)nor carotid pulse wave velocity in beginning of systole(PWV-BS)was found between groups(both P＞0.05).Carotid PWV-ES in HT group was positively correlated with patients'age,body mass index,TPOAb,TC,triglyceride,NLR and CIMT(r=0.217-0.707,all P＜0.05).Patients'age,TPOAb and NLR were all independent impact factors of increased carotid PWV-ES in HT patients with euthyroidism(all P＜0.05).Conclusion UFPWV technique could be used to evaluate changes of carotid artery elasticity in HT patients with euthyroidism,among which PWV-ES was relatively sensitive.
