Correlations of transcranial sonography of substantia nigra characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease
10.13929/j.issn.1003-3289.2024.08.009
- VernacularTitle:帕金森病患者经颅黑质超声特征与MRI黑质铁沉积表现的相关性
- Author:
Quan ZOU
1
;
Fei CHEN
;
Wenyu MENG
;
Hong ZHENG
Author Information
1. 兰州大学第一医院超声医学科,甘肃兰州 730000
- Keywords:
Parkinson disease;
substantia nigra;
iron;
ultrasonography;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2024;40(8):1160-1163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlations of transcranial sonography of substantia nigra(SN-TCS)characteristics with MRI iron deposition on substantia nigra in patients with Parkinson disease(PD).Methods Data of SN-TCS and craniocerebral MRI in 120 PD patients were retrospectively analyzed.The patients were divided into iron deposition positive group(positive group,n=46)and iron deposition negative group(negative group,n=74)according to quantitative susceptibility mapping(QSM)value.Then parameters of SN-TCS and MRI were compared between groups(both P＜0.05),and correlation analysis were also performed.Results The proportion of high echo positive,strong echo area and QSM value of substantia nigra,as well as of hyper-substantia nigra area/midbrain area(S/M)in positive group were all higher than those in negative group(all P＜0.001).No significant difference of midbrain area was found between groups(P＞0.05).Strong echo area of substantia nigra and S/M based on SN-TCS were both low-medium positively correlated with substantia nigra QSM value showed on MRI(r=0.497,0.529,both P＜0.001).Conclusion SN-TCS characteristics of PD patients were correlated with MRI iron deposition on substantia nigra,among which strong echo area and S/M were valuable for evaluating iron deposition on substantia nigra.
