Prenatal ultrasonic manifestations of congenital pulmonary airway malformation and bronchopulmonary sequestration for predicting adverse outcomes of neonates
10.13929/j.issn.1003-3289.2024.07.021
- VernacularTitle:先天性肺气道畸形与支气管肺隔离症产前超声表现用于预测新生儿不良转归
- Author:
Tiantian HUANG
1
;
Deming KONG
;
Haiyan XIAO
;
Weizhong WEI
Author Information
1. 华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)妇幼超声科,湖北武汉 430019
- Keywords:
congenital abnormalities;
lung;
bronchopulmonary sequestration;
infant,newborn;
ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2024;40(7):1062-1066
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of prenatal ultrasonic manifestations of congenital pulmonary airway malformation(CPAM)and bronchopulmonary sequestration(BPS)for predicting adverse outcomes of neonates.Methods Data of 51 singletons with CP AM,BPS or mixed malformations were retrospectively analyzed.The prenatal ultrasonic manifestations were observed,and the pulmonary mass volume to head circumference ratio(CVR)were measured.Receiver operating characteristic curves were drawn,the area under the curves(AUC)were calculated,and the efficacy of CVR for predicting adverse outcomes of neonates was evaluated.Results Pulmonary mass were detected in all 51 fetuses by prenatal ultrasound,with an average maximum diameter of(35.9±12.3)mm.Mediastinal displacement was observed in 28 fetuses(28/51,54.90％),pleural effusion and polyhydramnios each in 3 fetuses(3/51,5.88％),while other extrapulmonary malformations were noticed in 5 fetuses(5/51,9.80％).No fetal edema was found.According to the feeding artery of the mass,CPAM was diagnosed in 29(29/51,56.86％)fetuses,BPS in 20(20/51,39.22％),and mixed lesions were diagnosed in 2 fetuses(2/51,3.92％).The AUC of the initial CVR(CVR1),the maximum CVR(CVR2)and the last CVR(CVR3)of fetal pulmonary mass for predicting occurrence of neonatal respiratory distress and lung surgery were 0.907-0.993.CVR3≥1.25 was an independent predictive factors for neonatal respiratory distress in fetuses with pulmonary masses(OR=40.000,P=0.016).Conclusion CPAM and BPS had typical prenatal ultrasonic manifestations.CVR was a reliable indicator for predicting adverse neonatal outcomes of fetuses with CPAM and/or BPS.
