Quantitative CT abdominal fat parameters combined with clinical-imaging comprehensive model for predicting recurrent acute pancreatitis
10.13929/j.issn.1003-3289.2024.07.016
- VernacularTitle:定量CT腹部体脂参数联合临床-影像学综合模型预测复发性急性胰腺炎
- Author:
Hui LUO
1
;
Yuxuan WANG
;
Qian ZHANG
;
Chunyu LIU
;
Chao REN
;
Jian ZHAI
Author Information
1. 皖南医学院第一附属医院放射科,安徽芜湖 241001
- Keywords:
pancreatitis;
recurrence;
tomography,X-ray computed;
adipose tissue
- From:
Chinese Journal of Medical Imaging Technology
2024;40(7):1036-1040
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of quantitative CT(QCT)abdominal body fat parameters combined with clinical-imaging model for predicting recurrent acute pancreatitis(RAP).Methods Data of 468 patients with acute pancreatitis(AP),including 207 cases of RAP(RAP group)and 261 cases of non-RAP(non-RAP group)were retrospectively analyzed.Clinical information,conventional CT manifestations and QCT parameters such as abdominal subcutaneous fat area(SFA),visceral fat area(VFA),total abdominal fat area(TFA),hepatic fat content and pancreatic fat content at the first visit were recorded or measured.Clinical characteristics,CT manifestations and QCT parameter values were compared between groups,and the independent factors for predicting RAP were selected with multivariate logistic regression analysis.Then a clinical-imaging model and a comprehensive model combining with QCT parameters were constructed,and their efficacies for predicting RAP were evaluated with receiver operating characteristic(ROC)curves,and the area under the curves(AUC)were calculated.Results Compared with non-RAP group,patients in RAP group were younger,had higher percentage of alcohol consumption,biliary stones and hyperlipidemia,as well as of distinct pancreatic margins on CT images,also higher VFA,TFA,liver fat content and pancreatic fat content(all P＜0.05).Alcohol consumption,hyperlipidemia,biliary stones,pancreatic margins and pancreatic fat content were all independent predictors of RAP,and the comprehensive model constructed based on these five had higher AUC(0.860)than clinical-imaging model constructed based on the previous 4 factors(0.701)and pancreatic fat content alone(0.770)(both P＜0.001).Conclusion QCT abdominal body fat parameters combined with clinical-imaging comprehensive model was effective for predicting the risk of RAP.
