CT manifestations of pneumocystis jirovecii pneumonia and cytomegalovirus pneumonia after allogeneic hematopoietic stem cell transplantation

VernacularTitle:异基因造血干细胞移植后耶氏肺孢子菌肺炎与巨细胞病毒性肺炎CT表现
Author: Min CHENG ¹ ; Hao CHEN ; Ye SUN ; Xuyang CAO ; Nan HONG
Author Information

1. 北京大学人民医院放射科,北京 100044
Keywords: pneumonia; hematopoietic stem cell transplantation; tomography,X-ray computed
From: Chinese Journal of Medical Imaging Technology 2024;40(7):1025-1029
CountryChina
Language:Chinese
Abstract: Objective To compare CT manifestations of pneumocystis jirovecii pneumonia(PCP)and cytomegalovirus pneumonia(CMVP)after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Methods Totally 21 PCP patients(PCP group)and 26 CMVP patients(CMVP group)after allo-HSCT were retrospectively enrolled,and CT findings were compared between groups.Results Significant differences of distribution patterns of ground glass opacity(GGO)and nodule lesions,lung cysts,the time of condition reached most severe,the proportion of cases with lesions absorption more than 50％ within 30 days,of cases with lesions completely absorbed and the first total severity score(TSS)of GGO were found between groups(all P＜0.05).Conclusion CT manifestations of PCP and CMVP after allo-HSCT were somehow similar,but GGO distributed widerly,with more lung cysts and better prognosis in the former,while GGO distrubuted relatively limitted with diffuse nodules and poor prognosis in the latter.