Consistency of 5.0T and 1.5T MR spectroscopy for quantitating proton density fat fraction of liver
10.13929/j.issn.1003-3289.2024.05.009
- VernacularTitle:5.0T与1.5T MR波谱定量肝脏质子密度脂肪分数的一致性
- Author:
Jianxian LIU
1
;
Zhensong WANG
;
Zhengyi LI
;
Xin WANG
;
Dan YU
;
Yanxing YANG
;
Chuanli CHENG
;
Chao ZOU
;
Shuo CHEN
;
Jie GAN
Author Information
1. 山东大学附属山东省立第三医院影像中心,山东济南 250032
- Keywords:
liver;
magnetic resonance spectroscopy;
prospective studies;
proton density fat fraction
- From:
Chinese Journal of Medical Imaging Technology
2024;40(5):677-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the consistency of 5.0T and 1.5T MR spectroscopy(MRS)for quantitating proton density fat fraction(PDFF)of liver.Methods Lipid emulsion models with lipid content of 0,5%,10%,15%,20%,25%and 30%were prepared.1H-MRS were collected using 5.0T and 1.5T MR scanners,respectively,and PDFF were obtained with jMRUI software.Totally 23 people,including 11 cases of fatty liver and 12 healthy adults were prospectively collected,and volume of interest(VOI)in the liver were selected to acquire 1H-MRS,and PDFF were obtained with jMRUI software and corresponding workstation,respectively.The consistencies of PDFF measured with different methods were analyzed.Results PDFF of lipid emulsion models with lipid content of 0,5%,10%,15%,20%,25%and 30%measured with jMRUI software and workstations based on 5.0T and 1.5T 1H-MRS all had good consistencies and being positively correlated,so were PDFF of liver tissue measured with jMRUI software and workstations based on 5.0T and 1.5T 1H-MRS.Conclusion 5.0T and 1.5T 1H-MRS had good consistency for quantitating liver PDFF.Measuring liver PDFF with workstation in clinical practice was helpful to simplifying workflow.