5.0T MRI for quantifying proton density fat fraction of liver

Jianxian Liu; Zhensong Wang; Xin Wang; Ning Tian; Peng Chen; Dan YU; Yanxing Yang; Chuanli Cheng; Chao Zou; Jie Gan

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5.0T MRI for quantifying proton density fat fraction of liver

VernacularTitle:基于5.0T MRI定量肝脏质子密度脂肪分数
Author: Jianxian LIU ¹ ; Zhensong WANG ; Xin WANG ; Ning TIAN ; Peng CHEN ; Dan YU ; Yanxing YANG ; Chuanli CHENG ; Chao ZOU ; Jie GAN
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1. 山东大学附属山东省立第三医院影像中心,山东济南 250032
Keywords: liver; adipose tissue; magnetic resonance imaging; fat fraction; prospective studies
From: Chinese Journal of Medical Imaging Technology 2024;40(5):671-676
CountryChina
Language:Chinese
Abstract: Objective To observe the value of 5.0T MRI for quantifying proton density fat fraction(PDFF)of liver.Methods Liver chemical shift encoded(CSE)MR scanning were prospectively performed using 5.0T,3.0T and 1.5T scanner in 30 volunteers,respectively,and CSE-PDFF were measured.Then MR spectroscopy(MRS)were performed using 5.0T and 1.5T scanner,respectively,and MRS-PDFF were also measured.The consistency of liver PDFF measured on different images was observed,and the value of 5.0T MRI for liver PDFF was analyzed.Results The overall consistencies of liver CSE-PDFF measured with 5.0T,3.0T and 1.5T MR scanner were all good(all ICC＞0.75,all P＜0.001).The consistency of liver CSE-PDFF based on 5.0T and 3.0T,1.5T MR scanner were both good(ICC=0.989,0.992,both P＜0.001).The overall consistencies of CSE-PDFF based on 5.0T MR and MRS-PDFF based on 5.0T and 1.5T MR were both good(both ICC＞0.75,both P＜0.001).CSE-PDFF had good consistency with MRS-PDFF based on same 5.0T MR scanner(ICC=0.988,P＜0.001),and CSE-PDFF based on 5.0T had good consistency with MRS-PDFF based on 1.5T MR scanner(ICC=0.978,P＜0.001).Conclusion 5.0T MRI had high value for quantifying liver PDFF.