5.0T MRI measurement of hippocampal formation subfield volumes in healthy adults
10.13929/j.issn.1003-3289.2024.05.003
- VernacularTitle:5.0T MRI测量健康成人海马结构亚区体积
- Author:
Zhensong WANG
1
;
Jianxian LIU
;
Zhangzhu LI
;
Xiangsen JIANG
;
Zudong YIN
;
Lei YU
;
Yuan GUO
;
Zhengyi LI
;
Qian ZHANG
;
Jie GAN
Author Information
1. 山东大学附属山东省立第三医院影像中心,山东济南 250031
- Keywords:
magnetic resonance imaging;
prospective studies;
hippocampal;
volume measurement
- From:
Chinese Journal of Medical Imaging Technology
2024;40(5):648-652
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of 5.0T MRI in measuring the volumes of hippocampal formation(HF)subfields in healthy adults.Methods Cranial high-resolution TIWI were prospectively obtained in 23 healthy adult volunteers using 5.0T and 3.0T MR scanners,respectively.HF was divided into 38 subfields,and then the volume of each subfield was measured using FreeSurfer software.The volumes of HF subfield based on 5.0T and 3.0T MR T1WI were compared,and the correlations of the outcomes were analyzed.Results Significant differences of the volumes of bilateral hippocampal tails,left parasubiculum,left molecular layer of hippocampal head,left granular cell-molecular layer-dentate gyrus head,right granular cell-molecular layer-dentate gyrus body,left cornu Ammonis(CA)1 head,left CA3 head,left CA4 head,right fimbria of hippocampus and left hippocampus amygdala transition area were found between 5.0T and 3.0T T1WI(all P＜0.05).The volumes of HF subfields measured based on 5.0T and 3.0T T1WI were moderately to highly positively correlated(all r＞0.5,all P＜0.01).Conclusion 5.0T MRI could be used to measure the volume of HF subfield in adults.
