Research Progress in the Role of the Ventral Tegmental Area-Medial Prefrontal Cortex Neural Circuit in the Regulation of Arousal

VernacularTitle:腹侧被盖区-内侧前额叶皮质神经环路在觉醒调控过程中作用的研究进展
Author: Mengnan HAO ^{1
,

2} ; Xiaoli LIANG ; Yi ZHANG
Author Information

1. 遵义医科大学第二附属医院麻醉科,贵州遵义 563000
2. 遵义医科大学贵州省麻醉与器官保护基础研究重点实验室,贵州遵义 563000
Keywords: ventral tegmental area; medial prefrontal cortex; neural circuit; arousal
From: Acta Academiae Medicinae Sinicae 2024;46(3):402-408
CountryChina
Language:Chinese
Abstract: There are mutual neural projections between the ventral tegmental area(VTA)and the me-dial prefrontal cortex(mPFC),which form a circuit.Recent studies have shown that this circuit is vital in regu-lating arousal from sleep and general anesthesia.This paper introduces the anatomical structures of VTA and mPFC and the roles of various neurons and projection pathways in the regulation of arousal,aiming to provide new ideas for further research on the mechanism of arousal from sleep and general anesthesia.