Nontuberculous Mycobacteria Associated with Penicilliosis Marneffei Infection in A Human Immunodeficiency Virus-negative Patient:Report of One Case and Literature Review
10.3881/j.issn.1000-503X.2018.01.021
- VernacularTitle:人免疫缺陷病毒抗体阴性播散性非结核分枝杆菌病合并马尔尼菲青霉菌病一例并文献复习
- Author:
Ailing LIU
1
;
Ying GE
;
Peng WANG
;
Ying JIANG
;
Xin GAO
;
Jinjing LIU
Author Information
1. 中国医学科学院北京协和医学院北京协和医院免疫内科
- Keywords:
non-tuberculous mycobacteria;
penicilliosis marneffei;
human immunodeficiency virus-negtive
- From:
Acta Academiae Medicinae Sinicae
2018;40(1):131-135
- CountryChina
- Language:Chinese
-
Abstract:
Disseminated nontuberculous mycobacterial (NTM) infection occurs mostly in immunocompromised hosts.Penicilliosis marneffei (PM) is a unique dimorphic fungal infection endemic in Southeast Asia.It is one of the commonest opportunistic infections among human immunodeficiency virus (HIV)-positive patients.There are rare reports about NTM associated with PM infection in non-HIV-infected individuals.Peking Union Medical College Hospital diagnosed a 45-year-old male patient who came from Guangxi Province.He complained of abdominal pain,generalized lymphadenopathy,weight loss,fever,and upper limb pain at presentation.He was HIV-negative,blood culture was positive for NTM,and the result of humerus specimen culture was PM.After treatment with anti-NTM drugs and itraconazole,his clinical status was improved.He remained symptom-free during the 2-year follow-up.
