Effect of Recombinant Epidermal Growth Factor on Corneal Epithelial Cells after Excision of Pterygium
- VernacularTitle:重组人表皮生长因子对翼状胬肉切除后角膜损伤的修复作用
- Author:
Hui HONG
1
;
Wei ZHANG
;
Ping LIU
;
Ping ZHU
Author Information
1. Beijing Friendship Hospital
- From:
Acta Academiae Medicinae Sinicae
2001;23(2):199-201
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of recombinant epidermal growth factor on the wounded corneal healing after excision of pterygium. Methods Simple and unrecurrent pterygiums were selected , excised and sewed up conjunctival flap under local anaesthesia and microscope. After operation two drops of EGF eyedrop were used, and five minutes later 0.3% Tarivid Eye Oint was used again, and then the operated eye was enswathed. Everyday the wound cornea was observed and the EGF eyedrop was used. Results The wound cornea healing time of control group was seven days and that of the EGF group was five days and gave a remarkable difference (P＜0.05). The same results were obtained after comparing the effective group and noneffective group, P＜0.05. Conclusions EGF eyedrop can accelerate proliferation and recovery of wound corneal epithelial cells. In the clinical trial, every body felt well and no side-effect was observed.
