Weekly Cyclophosphamide Pulse Therapy Combined with Corticosteroids in the Treatment of Pemphigus
- VernacularTitle:环磷酰胺每周静脉冲击与皮质类固醇联合治疗天疱疮
- Author:
Guo-Quan JIA
1
;
Zhi-Qiang CHEN
;
He-Lian LI
;
Pan-Gen CUI
;
Wen-Yan XU
Author Information
1. Institute of Dermatology
- From:
Acta Academiae Medicinae Sinicae
2001;23(2):173-175
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the better regimen of combined cyclophosphamide pulse therapy with corticosteroids in the treatment of Pemphigus. Methods Intravenous cyclophosphamide was given weekly in a dosage of 600 mg to those Pemphigus patients whose conditions couldn't be improved by corticosteroids (oral prednisone 1.2～1.5 mg/kg/d) alone. Results Ten patients with Pemphigus received weekly cyclophosphomide therapy in addition to corticosteroid. Patients conditions improved quickly, without side effects. Conclusions Cyclophosphamide weekly pulse therapy combined with corticosteroids is a good regimen in the treatment of Pemphigus.
