New perspectives and prospects of ferroptosis in the research of skin diseases
10.3760/cma.j.cn431274-20240705-01041
- VernacularTitle:铁死亡在皮肤疾病研究中的新视角与展望
- Author:
Ningning TANG
1
;
Xiaoyuan HUANG
;
Yang LIU
;
Fuying LI
;
Dan XU
;
Chi ZHONG
;
Jianda ZHOU
Author Information
1. 湘雅常德医院整形美容科,常德 415000
- Keywords:
Ferroptosis;
Skin diseases
- From:
Journal of Chinese Physician
2024;26(9):1438-1440
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis is regarded as a novel and regulatable form of cell death, with its main characteristics being abnormal iron metabolism and the accumulation of lipid peroxides. Although there have been breakthroughs in the research of ferroptosis in tumors and degenerative diseases, its research in skin diseases is relatively scarce. Starting from the development of the concept of ferroptosis, this article expounds the basic characteristics and regulatory mechanisms of ferroptosis. In the field of skin diseases, we emphasize the importance of ferroptosis and discuss in detail the research and application of ferroptosis in various skin diseases, aiming to provide effective guidance for the treatment and clinical practice of various skin diseases, and offer new ideas for the future research direction of skin diseases.