Research progress of SGK1 in digestive system diseases
10.3760/cma.j.cn431274-20230827-00168
- VernacularTitle:SGK1在消化系统疾病中的研究进展
- Author:
Xixi BIAN
1
;
Dehuai JING
;
Guangxi ZHOU
;
Fengqin ZHU
Author Information
1. 济宁医学院临床医学院，济宁 272067
- Keywords:
Digestive system diseases;
Serum and glucocorticoid-regulated kinase 1
- From:
Journal of Chinese Physician
2024;26(9):1433-1437
- CountryChina
- Language:Chinese
-
Abstract:
Serum and glucocorticoid-inducible kinases (SGKs) are serine threonine protein kinases involved in the regulation of multiple signal transduction pathways in vivo. SGKs include SGK1, SGK2 and SGK3. SGK1 plays a crucial role in the development of diseases such as digestive inflammation and tumors by regulating inflammatory and immune responses through phosphorylation. This article briefly introduces the structure and function of SGK1, and describes the research progress and clinical significance of SGK1 in digestive diseases.
