The effect of Shuanghuakun pregnancy formula combined with thunder fire moxibustion on clinical symptoms and ovarian function in patients with endometriosis
10.3760/cma.j.cn431274-20231123-00593
- VernacularTitle:双花坤孕方联合雷火灸对子宫内膜异位症患者临床症状及卵巢功能的影响
- Author:
Qingyu LU
1
;
Hongwei JIA
Author Information
1. 河北省中医药科学院妇科，石家庄 050011
- Keywords:
Endometriosis;
Shuanghuakun pregnant formula;
Lightning moxibustion;
Ovarian function
- From:
Journal of Chinese Physician
2024;26(9):1360-1363
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effects of Shuanghuakun pregnancy formula combined with thunder fire moxibustion on clinical symptoms and ovarian function in patients with endometriosis (EMT).Methods:A retrospective study was conducted on 90 patients with EMT who visited Hebei Academy of Traditional Chinese Medicine and Shijiazhuang Hospital of Traditional Chinese Medicine from July 2021 to July 2023. They were divided into two groups, with 45 patients in each group, based on different treatment methods. The control group was treated with gestrinone capsules, while the observation group was treated with Shuanghuakun pregnancy formula combined with thunder fire moxibustion. The clinical efficacy, clinical symptom scores, ovarian function, and serum cytokines before and after treatment were compared between the two groups.Results:The total effective rate of the observation group [95.56%(43/45)] was higher than that of the control group [68.89%(31/45)] ( P<0.05). After treatment, the observation group had lower scores of non menstrual anal pain, sexual pain, non menstrual lower abdominal pain, and menstrual abdominal pain than the control group (all P<0.05). After treatment, the serum follicle stimulating hormone (FSH) level in the observation group was lower than that in the control group ( P<0.05), and the number of antral follicles and ovarian volume were greater than those in the control group (all P<0.05). After treatment, the levels of serum carbohydrate antigen 125 (CA125), tumor necrosis factor -α (TNF-α), and vascular endothelial growth factor (VEGF) in the observation group were lower than those in the control group (all P<0.05). Conclusions:The combination of Shuanghuakun pregnancy formula and thunder fire moxibustion can effectively alleviate symptoms such as abdominal pain in EMT patients, improve ovarian function, reduce serum FSH, CA125, TNF-α, and VEGF levels, and enhance treatment efficacy.
