The efficacy and safety of endoscopic submucosal tumor resection without labeling and submucosal injection for the treatment of gastric small gastrointestinal stromal tumors
10.3760/cma.j.cn431274-20240701-01012
- VernacularTitle:不行标记和黏膜下注射的内镜黏膜下肿瘤挖除术治疗胃小胃肠间质瘤的疗效和安全性
- Author:
Zhenguang CHEN
1
;
Yao LUO
;
Jinyuan YU
;
Songyang WU
;
Ning WU
;
Zaiyuan YE
Author Information
1. 浙江树人大学树兰国际医学院附属树兰（杭州）医院胃肠外科，杭州 310022
- Keywords:
Gastrointestinal stromal tumors;
Endoscopic submucosal excavation
- From:
Journal of Chinese Physician
2024;26(8):1146-1150
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy and safety of endoscopic submucosal tumor resection without labeling and submucosal injection (NMSI-ESE) in the treatment of gastric small gastrointestinal stromal tumors.Methods:A retrospective analysis was conducted on the clinical data of 49 patients diagnosed with gastric small gastrointestinal stromal tumors in the Department of Gastrointestinal Surgery at the Shulan (Hangzhou) Hospital from January 2019 to December 2023. Among them, 23 cases underwent NMSI-ESE and 26 cases underwent traditional endoscopic submucosal tumor resection (ESE). We compared the clinical and pathological characteristics, surgical time, tumor removal time, number of metal clips used, surgical costs, postoperative hospitalization time, and incidence of complications between two groups of patients.Results:Compared with the ESE group, the NMSI-ESE group had shorter surgical time [38.95(26.50, 53.25)min vs 47.30(38.50, 52.25)min, Z=-2.60, P=0.011], shorter tumor removal time [17.27(8.75, 24.50)min vs 27.08(18.75, 35.00)min, Z=-4.32, P<0.001], and lower surgical costs [3 308(3.190, 3 450)yuan vs 4 107(3 972, 4 232)yuan, Z=-20.95, P<0.001], fewer metal clips used [(3.86±0.91) vs (5.04±1.22), t=-4.00, P<0.001], and shorter postoperative hospitalization time [3.1(2.0, 4.0)d vs 3.5(3.0, 4.0)d, Z=-2.20, P=0.031], There was no statistically significant difference in R0 resection rate and postoperative complications (all P>0.05). During the follow-up period, both groups of patients had no tumor recurrence or metastasis. Conclusions:NMSI-ESE is safe and effective in treating small gastrointestinal stromal tumors, and can shorten surgical and hospitalization time, as well as reduce medical costs compared to traditional ESE.
