A meta-analysis of the efficacy and safety of non-invasive high-frequency oscillatory ventilation compared to nasal continuous positive airway pressure ventilation in neonates with respiratory distress syndrome after evacuating invasive ventilators
10.3760/cma.j.cn431274-20231118-00568
- VernacularTitle:无创高频振荡通气对比经鼻持续气道正压通气在新生儿呼吸窘迫综合征撤离有创呼吸机后疗效及安全性的meta分析
- Author:
Lin YAN
1
;
Hua MEI
;
Yuheng ZHANG
;
Mengyue HUO
;
Xiaoli WANG
Author Information
1. 内蒙古医科大学附属医院新生儿科，呼和浩特 010050
- Keywords:
Respiratory distress syndrome, newborn;
Noninvasive high-frequency oscillatory ventilation;
Nasal continuous positive airway pressure;
Meta-analysis
- From:
Journal of Chinese Physician
2024;26(5):686-691
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of non-invasive high-frequency oscillatory ventilation (nHFOV) and nasal continuous positive airway pressure ventilation (nCPAP) as transitional breathing modes after evacuation from invasive ventilation in neonatal respiratory distress syndrome (NRDS).Methods:A randomized controlled trial was conducted using PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Wanfang, and VIP databases to search for all published literature before July 2022 on the treatment of NRDS with nHFOV and/or nCPAP after invasive ventilation and weaning. We compared the success rates of the evacuation , as well as the incidence of pneumothorax, bronchopulmonary dysplasia, and intraventricular hemorrhage between the nHFOV group and the nCPAP group in newborns who underwent invasive ventilation with NRDS.Results:A total of 7 randomized controlled studies were included, including 598 newborns diagnosed with NRDS who underwent tracheal intubation mechanical ventilation. The success rates of evacuating invasive ventilators for children in the nHFOV and nCPAP groups included in the article were calculated. The success rates of evacuating invasive ventilators for children in the two groups were 88.5%(231/261) and 66.5%(171/257), respectively. Compared with the nCPAP group, the success rate of evacuating invasive ventilators for children with NRDS in the nHFOV group was higher ( OR=3.93, 95% CI: 2.47-6.23, P<0.001). However, there was no statistically significant difference in the incidence of bronchopulmonary dysplasia, intraventricular hemorrhage, and pneumothorax between the two groups after weaning (all P>0.05). Conclusions:After weaning NRDS patients with invasive ventilation, nHFOV has a higher success rate in weaning compared to nCPAP, which is worthy of clinical application.
